Status:

COMPLETED

Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia

Lead Sponsor:

Brigham and Women's Hospital

Collaborating Sponsors:

Mclean Hospital

Harvard School of Public Health (HSPH)

Conditions:

Tuberculosis

Alcohol Use Disorders

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The primary goal of this study is to assess the effectiveness of two alcohol interventions administered singly or in combination as an integrated component of TB care provided to patients with co-occu...

Detailed Description

An important aspect of the delivery of these alcohol interventions will be their incorporation into TB care and delivery by non-alcohol specialists, i.e. TB physicians. In this study, we propose to ex...

Eligibility Criteria

Inclusion

  • Are newly diagnosed with Pulmonary TB: infiltrative, disseminated, or other forms of TB in phase of disintegration
  • Will initiate TB treatment in one of 7 study sites (Tomsk Oblast TB Hospital, polyclinic, day hospital, and raions)
  • Are 18 years and older
  • Are diagnosed with alcohol abuse and dependence by the CIDI-SAM; and
  • Signed informed consent

Exclusion

  • Have liver function tests more than 3x the upper limit of normal range. The participant can be retested after 5 days; if any of the repeat liver function tests is more than 3x upper limit of normal range, the person is excluded
  • Reported opioid use in the past month or positive during screen for opioids. The participant can be retested after 5 days; if the second urine screen is positive, the person is excluded;
  • Are pregnant or breastfeeding;
  • Demonstrate inadequate understanding of the study after undergoing informed consent; or
  • Have any co-occurring other medical or psychiatric condition that would make it impossible for them to comply with the study procedures.

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00675961

Start Date

January 1 2007

End Date

June 1 2011

Last Update

October 25 2017

Active Locations (1)

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Tomsk Oblast TB Services

Tomsk, Tomsk Oblast, Russia