Status:
WITHDRAWN
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children
Lead Sponsor:
Medical College of Wisconsin
Conditions:
Non-Alcoholic Steatohepatitis
Eligibility:
All Genders
2-18 years
Brief Summary
The purpose of this study is to document how often specific genotypes known to be associated with adult-onset NASH (Non-Alcoholic Steatohepatitis) occur in a pediatric cohort and investigate whether t...
Detailed Description
NASH is a clinico-pathological entity characterized by the development of histological changes of inflammation and fibrosis in the liver that are nearly identical to those induced by excessive alcohol...
Eligibility Criteria
Inclusion
- All subjects aged 2-18 with biopsy proven NAFLD and/or NASH undergoing a blood draw and willing to consent to this study will qualify for inclusion in this protocol.
Exclusion
- other causes of chronic liver disease or other chronic diseases, specifically autoimmune disorders, immunodeficiencies, or individuals with congenital/genetic disorders
- chronic viral hepatitis, Wilson's disease, or alpha -1- antitrypsin deficiency
- acute life threatening illness or conditions
Key Trial Info
Start Date :
May 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2016
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00677183
Start Date
May 1 2008
End Date
May 1 2016
Last Update
August 25 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States, 53226