Status:
COMPLETED
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Lead Sponsor:
Sunnybrook Health Sciences Centre
Conditions:
Total Knee Arthroplasty
Post Operative Analgesia
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty. Numerous studies have demonstrated that nerve bl...
Detailed Description
The objectives of this study are: 1. Evaluate the role of sciatic nerve block in total knee replacement. There is conflicting data as to whether sciatic nerve block would provide significant analgesi...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical status I and III
- Scheduled for total knee arthroplasty
Exclusion
- Patients not providing informed consent.
- Refusal of treatment plan.
- Preexisting medical/neurological/hematologic conditions contraindicated for spinal anesthesia or peripheral nerve blocks.
- Revision total knee arthroplasty.
- Known allergy to any of the medications being used.
- History of drug or alcohol abuse.
- Patients with chronic pain on slow-release preparations of opioid in excess of 30mg of morphine equivalence per day.
- Patients with Rheumatoid Arthritis.
- Patients with psychiatric disorders.
- Patients unable or unwilling to use Patient Controlled Analgesia.
- Diabetic patients or those with impaired renal function (Creatinine \>106).
- Obese patients (i.e. BMI \>45).
- Postoperatively, patients will be excluded if they have had additional operative procedures requiring a change in the usual rehabilitation protocol of care.
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT00677261
Start Date
June 1 2008
End Date
November 1 2012
Last Update
November 21 2014
Active Locations (1)
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1
Holland Orthopedic and Arthritic Centre
Toronto, Ontario, Canada, M2N-3Y7