Status:
COMPLETED
Low Doses of Cholestyramine in the Treatment of Hyperthyroidism
Lead Sponsor:
Shiraz University of Medical Sciences
Conditions:
Graves Disease
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
The enterohepatic circulation of thyroid hormones is increased in thyrotoxicosis.Bile-salt sequestrants (ionic exchange resins) bind thyroid hormones in the intestine and thereby increase their fecal ...
Detailed Description
The gastrointestinal tract has a role in thyroid physiology. Thyroid hormone is metabolized mainly in the liver, where it is conjugated to glucurunides and sulfates. These conjugation products are the...
Eligibility Criteria
Inclusion
- Patients with newly diagnosed hyperthyroid Graves' disease
Exclusion
- If the patient had been treated previously
- diabetes, kidney, or liver disease
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2008
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00677469
Start Date
July 1 2007
End Date
January 1 2008
Last Update
May 14 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Endocrine and Metabolism Research Center
Shiraz, Fars, Iran