Status:
COMPLETED
Gluten-free Diet in Gluten-genetically Predisposed Subjects
Lead Sponsor:
IRCCS Burlo Garofolo
Collaborating Sponsors:
University of Trieste
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Conditions:
Genetic Predisposition to Disease
Celiac Disease
Eligibility:
All Genders
Phase:
NA
Brief Summary
Undetected or untreated CD may cause severe complications later in life, such as autoimmune disorders. It is recommended for subjects with autoimmune diseases or at risk for CD to be screened for CD ...
Detailed Description
Celiac disease (CD) is an autoimmune enteropathy triggered by ingestion of gluten in genetically susceptible subjects and is one of the most frequently occurring, treatable, lifelong disorders. In thi...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- first degree relatives of CD patients
- subjects with autoimmune disease tested negative for serum anti-tTG but positive for CD related HLA DQ2 or DQ8
- symptomatic subjects (genetically predisposed to gluten intolerance) tested negative for CD related autoantibodies and with apparently normal intestinal mucosa.
- Exclusion criteria:
- \- None
Exclusion
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00677495
Start Date
May 1 2007
End Date
June 1 2020
Last Update
September 3 2020
Active Locations (1)
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1
IRCCS Burlo Garofolo
Trieste, Friuli Venezia Giulia, Italy, 34137