Status:

COMPLETED

Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer

Lead Sponsor:

Pfizer

Conditions:

Kidney Neoplasms

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The study is designed to demonstrate that axitinib (AG-013736) is superior to sorafenib in delaying tumor progression in patients with metastatic renal cell cancer after failure of one first line regi...

Eligibility Criteria

Inclusion

  • Histologically or cytologically confirmed renal cell cancer with a component of clear cell subtype, with metastasis
  • Evidence of measurable disease
  • Must have failed one prior systemic first-line regimen for metastatic renal cell cancer

Exclusion

  • Prior treatment for metastatic renal cell cancer with more that one systemic first line therapy
  • Major surgery less than 4 weeks or radiation less than 2 weeks of starting study drug

Key Trial Info

Start Date :

September 3 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 25 2016

Estimated Enrollment :

723 Patients enrolled

Trial Details

Trial ID

NCT00678392

Start Date

September 3 2008

End Date

February 25 2016

Last Update

January 9 2019

Active Locations (294)

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Page 1 of 74 (294 locations)

1

East Valley Hematology and Oncology Medical Group

Burbank, California, United States, 91505

2

Maurice Berkowtiz, MD

Burbank, California, United States, 91505

3

Agajanian Institute of Oncology and Hematology

Downey, California, United States, 90241

4

Los Angeles Hematology/Oncology Medical Group

Glendale, California, United States, 91206