Status:

COMPLETED

A Multiple Ascending Dose Study of RO4998452 in Patients With Type 2 Diabetes Mellitus.

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Diabetes Mellitus Type 2

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of RO4998452 compared to placebo in patients with type 2 diabetes mellitus. Success...

Eligibility Criteria

Inclusion

  • adult patients, 18-65 years of age;
  • type 2 diabetes;
  • either treated by diet and exercise alone or with metformin.

Exclusion

  • type 1 diabetes mellitus;
  • uncontrolled hypertension;
  • clinically severe diabetic complications.

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2009

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT00682097

Start Date

May 1 2008

End Date

March 1 2009

Last Update

November 2 2016

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Chula Vista, California, United States, 91911

2

San Antonio, Texas, United States, 78229

3

Neuss, Germany, 41460