Status:
COMPLETED
Low-Dose Aspirin in in Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) Treatments
Lead Sponsor:
University of Oulu
Collaborating Sponsors:
Bayer
Kuopio University Hospital
Conditions:
Pregnancy
Miscarriage Less Than 12 Gestational Weeks
Eligibility:
FEMALE
18-39 years
Phase:
NA
Brief Summary
In this study we hypothesized that low-dose aspirin therapy (100 mg daily) improves ovarian responsiveness, uterine haemodynamics and clinical pregnancy rates in unselected subjects undergoing IVF/ICS...
Detailed Description
Low-dose acetylsalicylic acid irreversibly inhibits the cyclo-oxygenase enzyme in platelets, thus preventing the synthesis of thromboxane, which causes vasoconstriction and platelet aggregation. By th...
Eligibility Criteria
Inclusion
- age \< 40 years
- \< 4 previous ovarian stimulations
Exclusion
- allergy for acetylsalicylic acid
Key Trial Info
Start Date :
March 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2006
Estimated Enrollment :
374 Patients enrolled
Trial Details
Trial ID
NCT00683202
Start Date
March 1 2001
End Date
March 1 2006
Last Update
May 23 2008
Active Locations (1)
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1
University Hospital of Oulu, Department of Obstetrics and Gynecology
Oulu, Finland, 90220