Status:

COMPLETED

Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders

Lead Sponsor:

Medical University of Vienna

Conditions:

Hepatitis C

Eligibility:

All Genders

19-70 years

Phase:

PHASE2

Brief Summary

By chance the investigators found that iv. silibinin has a potent antiviral effect against the hepatitis C virus. Based on the results of the dose finding study (published) te optima dosing schedule i...

Detailed Description

Since the publication of the first data the optimal dosing schedule is investigated

Eligibility Criteria

Inclusion

  • Nonresponders to full dose PEG-IFN/RBV therapy
  • Liver biopsy within the last 2 year

Exclusion

  • Intolerance to one of the study drugs
  • Coinfection with HIV/HBV

Key Trial Info

Start Date :

October 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00684268

Start Date

October 1 2007

End Date

June 1 2011

Last Update

March 27 2017

Active Locations (1)

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Medical University of Vienna

Vienna, Austria, A1090