Status:
COMPLETED
Employment-Based Depot Naltrexone Clinical Trial II
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Opiate Dependence
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether employment-based naltrexone treatment proves effective in promoting depot naltrexone adherence and drug abstinence.
Detailed Description
A randomized study is planned to evaluate the effectiveness of employment-based reinforcement in promoting depot naltrexone adherence in opiate-dependent adults. Vivitrol, an extended-release depot fo...
Eligibility Criteria
Inclusion
- Individuals were eligible if they:
- met the Diagnostic and Statistical Manual (DSM)-IV criteria for opioid dependence,
- reported using heroin at least 21 of the last 30 days while living in the community,
- were unemployed,
- were 18-65 years old,
- were medically approved for naltrexone,
- lived in or near Baltimore, MD.
- Individuals were excluded if they:
- were pregnant or breastfeeding,
- had serum aminotransferase levels over three times normal,
- had current hallucinations, delusions, or thought disorders, current suicidal or -homicidal ideation,
- expressed interest in methadone treatment,
- were required to use opioids for medical purposes,
- earned over $200 in taxable income over the previous 30 days,
- had physical limitations that would prevent them from using a keyboard, or were incarcerated or under constant monitoring by the criminal justice system.
Exclusion
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2010
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00684775
Start Date
May 1 2008
End Date
April 30 2010
Last Update
January 23 2018
Active Locations (1)
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1
The Center for Learning and Health
Baltimore, Maryland, United States, 21224