Status:
COMPLETED
Fluid Balance, Hormones and Urine Proteomics in Nephrotic Syndrome in Childhood
Lead Sponsor:
Aarhus University Hospital
Collaborating Sponsors:
The Danish Medical Research Council
The Danish Kidney Association
Conditions:
Nephrotic Syndrome
Eligibility:
All Genders
1-15 years
Brief Summary
The purpose of this study is to describe the hormones controlling fluid balance in pediatric patients with nephrotic syndrome. Further more, an analysis of the urinary and plasma proteins will be done...
Detailed Description
Nephrotic syndrome represents the association of proteinuria, hypoalbuminemia, oedema and hyperlipidemia. The pathogenesis of the oedemas remains controversial. The "underfill" theory is the tradition...
Eligibility Criteria
Inclusion
- Idiopathic Nephrotic syndrome, age below 15 years
Exclusion
- Systemic disease e.g. Henoch-Schonleins purpura, Lupus erythematosus, diabetes mellitus
- Age over 15 years
- Treatment with diuretics prior to baseline blood samples
Key Trial Info
Start Date :
December 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT00690586
Start Date
December 1 2007
End Date
May 1 2010
Last Update
June 8 2010
Active Locations (1)
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1
Department of Pediatrics, Aarhus University Hospital, Skejby
Aarhus, Aarhus N, Denmark, 8200