Status:
WITHDRAWN
Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Alzheimer's Disease
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
University Hospital, Bonn
Conditions:
Alzheimer's Disease
Glaucoma
Eligibility:
All Genders
18-75 years
Brief Summary
Glaucoma is a worldwide leading cause of blindness. The key feature of this ocular neuropathy is characterized by an excavating optic nerve head. Loss of retinal ganglion cells is the final end point ...
Detailed Description
Hypothesis: Differences in the proteome concerning cell death pathways of glaucoma patients correspond to the differences in the mRNA expression of these patients. Specific aims: Characterization o...
Eligibility Criteria
Inclusion
- German native speakers
- Age between 18-85 years
- Primary open-angle glaucoma (POAG) with and without vasospasm
- An inclusion criterion for one control group is Alzheimer's disease.
Exclusion
- Any history of:
- Ocular or systemic diseases other than glaucoma or Alzheimer's disease
- Drug or alcohol abuse
- Any condition potentially interfering with the visual field results. Visual fields will be obtained from the chart.
- Mental impairment interfering with the ability to cooperate and understand the purpose of this study.
Key Trial Info
Start Date :
June 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00691340
Start Date
June 1 2008
End Date
August 1 2011
Last Update
March 10 2015
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