Status:
COMPLETED
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia
Lead Sponsor:
Wake Forest University
Conditions:
Central Centrifugal Scarring Alopecia
Lichen Planopilaris
Eligibility:
FEMALE
30+ years
Brief Summary
The purpose of this research study is to see if a specific protein that we are interested in is involved in scarring hair loss. If these proteins are involved, further genetic work may also better def...
Detailed Description
This is a single-center study, designed to evaluate the expression of Fas protein in skin biopsies of patients with scarring alopecia including fourteen patients with central centrifugal scarring alop...
Eligibility Criteria
Inclusion
- Participants ages 30 years or older with a biopsy- proven diagnosis of CCSA.
- Undergone standard of care treatment for CCSA by a WFUSM Dermatologist
- Women of child bearing age will be required to have a negative pregnancy test in order to participate in the study
- Participants ages 30 years or older with a biopsy- proven diagnosis of LP.
- Participants ages 30 years or older with a biopsy- proven diagnosis of DLE.
- Healthy participants must be ages 30 years or older.
Exclusion
- Age less than 30 years of age.
- Clinically evident bacterial or viral infection of the scalp.
- Pregnant or nursing woman of child-bearing potential.
- Participation in any other investigative research study involving study medication.
- Inability to return for the biopsy visit.
Key Trial Info
Start Date :
April 26 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 26 2012
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00691769
Start Date
April 26 2006
End Date
November 26 2012
Last Update
July 6 2018
Active Locations (1)
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1
Wake Forest University Health Sciences Dermatology
Winston-Salem, North Carolina, United States, 27157