Status:

COMPLETED

Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial

Lead Sponsor:

Shanghai Institute of Planned Parenthood Research

Collaborating Sponsors:

Shanghai Municipal Commission of Health and Family Planning

Fudan University

Conditions:

Healthy

Eligibility:

FEMALE

20-45 years

Phase:

PHASE2

Brief Summary

A multicentric clinical trial in three Chinese Maternal and Child Hospitals was conducted to evaluate the efficacy, safety and acceptability of newly-developed vaginal contraceptive gel, the optimized...

Detailed Description

A phase II, multicentric,randomized, controlled clinical trial.

Eligibility Criteria

Inclusion

  • at risk for pregnancy and desiring contraception
  • having regular menstrual cycle (21-35 days)
  • at low risk for HIV or other sexually transmitted infection
  • sexually active
  • use the test products as their primary method of contraception
  • keep a diary of coital activity, product use, and adverse events

Exclusion

  • diagnosis of any vaginal infection or any symptom of STDs at baseline
  • known allergy or hypersensitivity to N-9 or BZK
  • menopause for more than one month
  • breastfeeding
  • vaginal bleeding with unknown reasons
  • genitourinary system anomaly
  • hysteroptosis II or severe cystocele
  • moderate to severe erosion of cervix
  • malignant reproductive system tumors

Key Trial Info

Start Date :

March 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2005

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00692952

Start Date

March 1 2004

End Date

November 1 2005

Last Update

July 10 2009

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Gynecology and Obstetrics Hospital of Fudan University

Shanghai, China

2

International Peace Maternity and Child Care Center

Shanghai, China

3

Shanghai No. 1 Maternity and Child Care Center

Shanghai, China