Status:
COMPLETED
Effects of Hoodia on Blood Pressure and Heart Function
Lead Sponsor:
University of Mississippi Medical Center
Conditions:
Healthy
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The purpose of the study is to learn about an herbal product called Hoodia gordonii. We want to know if Hoodia gordonii affects blood pressure, heart rate (pulse), heart pressures, and the heart's ele...
Detailed Description
If you decide to join this research study you will come in for two visits one week apart. Each visit will last 8 hours (you will not be required to stay in the exam room for the entire day). During th...
Eligibility Criteria
Inclusion
- Subjects at least 18 years of age and in general good health expressing interest in participating in the study will be evaluated for inclusion.
Exclusion
- baseline heart rate less than 50 beats/minute or greater than 100 beats/minute
- heart rhythm other than normal sinus
- history of atrial or ventricular arrhythmia
- family history of premature sudden cardiac death
- left ventricular hypertrophy
- atherosclerosis
- hypertension
- palpitations
- T-wave abnormality
- baseline corrected QT(QTc) interval greater than 440 milliseconds (ms)
- thyroid disease
- type 1 or 2 diabetes mellitus
- recurrent headaches
- depression
- any psychiatric condition or neurological disorder
- history of alcohol or drug abuse
- renal or hepatic dysfunction
- concurrent use of potentially interacting drugs (anticoagulants, MAO inhibitors, CYP 3A impacted drugs (substrate, inducer, or inhibitor) over the counter medications containing pseudoephedrine, caffeine containing products, or any dietary supplements)
- subject unwillingness to sign informed consent
- Pregnant or lactating females will also be also excluded from participation with urine dipstick tests used to confirm lack of pregnancy.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00693264
Start Date
May 1 2008
End Date
July 1 2008
Last Update
March 30 2009
Active Locations (1)
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1
University of Mississippi Medical Center
Jackson, Mississippi, United States, 39216