Status:
COMPLETED
Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Obesity and Type 2 Diabetes
Eligibility:
FEMALE
14-18 years
Phase:
NA
Brief Summary
The overall goal of this project is to examine the physiological and metabolic effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral com...
Eligibility Criteria
Inclusion
- At Risk of Overweight and Overweight (age- \& sex-specific body mass index ≥ 85th percentile based on CDC BMI growth charts \[US Department of Health and Human Services, 2000\]. There will not be an upper BMI limit. In our experience, we have had numerous children above the 99th percentile for BMI complete the outcome measures, and this group could benefit greatly from participation.
- Gender \& Age: Females from grades 9th to 12th (approximately 14-18 years of age). We chose to study adolescents because pubertal youth will likely possess the requisite hormonal milieu needed to elicit physiologically and metabolic changes in response to resistance and aerobic training. In addition physical activity declines are more pronounced in minority females. By limiting the study to just females, we will retain a more homogenous group. This will eliminate sensitive gender issues related to exercise such as body image concerns, goal setting, and motivations for behavioral changes. To reduce effects of the menstrual cycle, all females will be tested during the follicular phase, while those with irregular/unpredictable menses will be studied at random times.
- Latino origin all four grandparents must be of Hispanic heritage (reported on screening forms). This approach is consistent with all of our previous and ongoing work.
Exclusion
- Presently taking medication(s) or diagnosed with any syndrome or disease that could influence physical activity, body composition and fat distribution, or insulin action.
- Previously diagnosed with any major illness since birth (e.g. chronic birth asphyxia, cancer, etc.).
- Children with type 1 and/or type 2 diabetes will be excluded and referred to a physician. Children with impaired glucose tolerance (fasting glucose \>100 mg/dL during a fasting blood draw) and/or conditions associated with insulin resistance (e.g. acanthosis nigricans, hypertension, dyslipidemia) will be eligible, as long as they are not receiving treatment and meet other eligibility criteria.
- Children who have any physical, cognitive, or psychological disabilities that would prevent them from participating in an exercise program.
- Currently, or in the past 6 months, involved with any dietary, physical activity or weight loss program.
- Children who live farther than 20 miles away from the GCRC.
Key Trial Info
Start Date :
October 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2012
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00693511
Start Date
October 1 2007
End Date
August 31 2012
Last Update
September 25 2017
Active Locations (1)
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1
Veronica Atkins Lifestyle Intervention Laboratory
Los Angeles, California, United States, 90033