Status:
COMPLETED
Contact Allergies to Dental Metal as a Possible Risk Factor for Oral Cancer
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
18+ years
Brief Summary
RATIONALE: Gathering information about allergies to metals may help doctors learn whether having an allergy to metal used in dental work increases the risk of developing oral cancer. PURPOSE: This cl...
Detailed Description
OBJECTIVES: * Identify the relationship between intraoral metal contact allergy and epithelial carcinogenesis in patients with newly or previously diagnosed intraoral squamous cell carcinoma. * Compa...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Meets 1 of the following criteria:
- Newly or previously diagnosed oral squamous cell carcinoma
- Recruited from the otorhinolaryngology departments of Mayo Clinic Rochester and Mayo Clinic Arizona
- Healthy volunteer (control)
- No history of intraoral squamous cell carcinoma
- Employed at Mayo Clinic Rochester or Mayo Clinic Arizona
- PATIENT CHARACTERISTICS:
- No immunosuppression
- No other conditions that interfere with patch testing
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
August 1 2000
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2009
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT00693550
Start Date
August 1 2000
End Date
January 1 2009
Last Update
June 8 2011
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905