Status:
COMPLETED
Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin
Lead Sponsor:
Oregon Health and Science University
Conditions:
Obesity
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to learn more about how diet affects the hormone ghrelin. Ghrelin is made in the stomach and causes appetite to increase. Learning about ghrelin will help the investigator...
Detailed Description
Control subjects will be provided 3 different diets for 2 weeks each. At the end of each diet period participants will be admitted to OHSU Clinical Translation Research Center (CTRC) for blood samplin...
Eligibility Criteria
Inclusion
- Age 18 or older.
- Weight stable for at least 3 months.
- At lifetime maximal body weight.
Exclusion
- Actively losing weight by diet or exercise.
- Smokers.
- Alcohol consumption \> 2 drinks per day.
- Exercise \> 30 minutes 3 times a week.
- Prescription drug use (except birth control pills, vitamins, or minerals).
- Type 2 diabetes.
- Heart disease, cancer, malabsorptive states, or chronic infections that would affect body weight.
- Weight \> 300 lbs (exceeds the weight limit of the DEXA machine).
- Hemoglobin \< 12.0 g/dL for women, \< 13.5 g/dL for men
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT00694512
Start Date
February 1 2008
End Date
March 1 2011
Last Update
May 15 2012
Active Locations (1)
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1
Oregon Health & Science University
Portland, Oregon, United States, 97239