Status:
COMPLETED
A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Liver Insufficiency
Eligibility:
All Genders
18-75 years
Phase:
PHASE1
Brief Summary
A study to compare the plasma concentrations of MK0431 at different times in patients with hepatic insufficiency vs healthy control subjects.
Eligibility Criteria
Inclusion
- If female, non pregnant, BMI less than 40 kg/m2
- Patient has chronic, stable hepatic insufficiency
Exclusion
- Patient unwilling to refrain from alcohol and grapefruit juice prior to and shortly after study drug administration
- Patient has diabetes, had a heart attack or stroke, or uncontrolled congestive heart failure during the past 6 months
- Patient has a history of drug or alcohol abuse
- Patient smokes \> 10 cigarettes per day
- Patient consumes more that 6 cups of caffeinated beverages per day
- Patient has had surgery, donated blood or participated in another clinical trial within the past 4 weeks
Key Trial Info
Start Date :
April 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2004
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00696826
Start Date
April 1 2004
End Date
May 1 2004
Last Update
August 19 2015
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