Status:
UNKNOWN
Radiotherapy Planning Based on Positron Emission Tomography With Fluoro-deoxyglucose For Advanced NSCLC
Lead Sponsor:
Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie der DEGRO und DGN
Conditions:
Non-small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Simultaneous radio-chemotherapy in advanced non-small cell lung cancer. The study focusses on a randomised comparison of conventional radiotherapy planning with irradiation of macroscopic tumor and ly...
Detailed Description
Simultaneous radio-chemotherapy in advanced non-small cell lung cancer. The study focusses on a randomised comparison of conventional radiotherapy planning with irradiation of macroscopic tumor and ly...
Eligibility Criteria
Inclusion
- histologically proved NSCLC
- UICC-stage I-III, no resection planned
- complete staging \< 6 wks before treatment including cranial CT
- ECOG \<3, Karnofsky-Index \>60%
- age \> 18 \<
- FEV1 \> 1,0 l or \>35%
- RT-planning according to protocol feasible
- chemotherapy feasible
- written informed consent
Exclusion
- neuroendocrine tumors, plain broncho-alveolar-cell ca.
- distant metastases, supraclavicular lymph node metastases
- malignant pleural effusion
- resection of actual tumor performed
- inclusion in other study protocol
- chemotherapy due to actual tumor before FDG-PET
- induction-chemotherapy
- acute vena cava superior syndrome
- second malignancy other than basalioma
- pregnancy, lactation
- heart insufficiency NYHA III/IV
- pneumoconiosis with active inflammatory changes of mediastinal lymph nodes
- acute broncho-pulmonary infection at time of PET-examination
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2017
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00697333
Start Date
May 1 2009
End Date
May 1 2017
Last Update
July 14 2016
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Universitätsklinikum Freiburg
Freiburg I. Br., Baden-Wurttemberg, Germany, D-79106
2
Universitätsklinikum Freiburg
Freiburg i.Br., Baden-Wurttemberg, Germany, D-79106