Status:
COMPLETED
Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis
Lead Sponsor:
Medical University of Lodz
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
6-18 years
Phase:
PHASE4
Brief Summary
The purpose of the trial is to compare the efficacy and safety of sublingual seasonal and annual immunotherapy in children with allergic rhinitis allergic to grass pollens.
Detailed Description
Allergen immunotherapy is currently the only one method of cause treatment of the IgE-dependent allergic diseases. Sublingual immunotherapy (SLIT) is the method which allows to give allergens via alte...
Eligibility Criteria
Inclusion
- Children with seasonal allergic rhinitis, allergic to grass pollens, first diagnosed at least 2 years before inclusion into the study
Exclusion
- Active upper respiratory tract infection within 3 weeks before the study and acute sinus disease requiring antibiotic treatment within 1 month before the study
- Allergic rhinitis hospitalisation during the 3 months before the first visit.
- Additional criteria were other clinically significant pulmonary, hematologic, hepatic, gastrointestinal, renal, endocrine, neurologic, cardiovascular, and/or psychiatric diseases or malignancy that either put the patient at risk when participating in the study or could influence the results of the study or the patient's ability to participate in the study as judged by the investigator.
- Excluded medications were systemic corticosteroids.
- Patients who were receiving immunotherapy were also excluded.
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00698594
Start Date
September 1 2008
End Date
March 1 2011
Last Update
August 22 2011
Active Locations (1)
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1
Department of Pediatrics and Allergy, Medical University of Lodz, Poland
Lodz, Łódź Voivodeship, Poland