Status:

COMPLETED

A Clinical Investigation of the Vanguard™ Complete Knee System

Lead Sponsor:

Zimmer Biomet

Conditions:

Osteoarthritis

Traumatic Arthritis

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this prospective clinical data-collection is to document the performance and clinical outcomes of the Vanguard™ Complete Knee System.

Detailed Description

This is a 10-year prospective observational data collection on the Vanguard Total Knee system. Patients are asked to come in for a preop, operative, immediate post-operative, 6 Month, 1 Year, 3 Year,5...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved.
  • Correction of varus, valgus, or posttraumatic deformity
  • Correction or revision of unsuccessful osteotomy, or arthrodesis
  • Patient selection factors to be considered include:
  • Need to obtain pain relief and improve function
  • Ability and willingness of the patient to follow instructions
  • Including control of weight and activity level
  • Good nutritional state of the patient
  • Patient must have reached full skeletal maturity
  • Exclusion criteria:
  • Absolute contraindications include:
  • Infection
  • Sepsis
  • Osteomyelitis
  • Failure of a previous joint replacement
  • Relative contraindications include:
  • Uncooperative patient or patient with neurologic disorders who are incapable of following directions
  • Osteoporosis
  • Metabolic disorders which may impair bone formation
  • Osteomalacia
  • Distant foci of infections which may spread to the implant site
  • Rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram
  • Vascular insufficiency, Muscular atrophy, Neuromuscular disease
  • Incomplete or deficient soft tissue surrounding the knee
  • Additional exclusion criteria includes: failure of a previous joint replacement

Exclusion

    Key Trial Info

    Start Date :

    March 1 2004

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2024

    Estimated Enrollment :

    552 Patients enrolled

    Trial Details

    Trial ID

    NCT00698854

    Start Date

    March 1 2004

    End Date

    March 1 2024

    Last Update

    September 19 2024

    Active Locations (8)

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    Page 1 of 2 (8 locations)

    1

    Physicians Clinic of Iowa Orthopedics

    Cedar Rapids, Iowa, United States, 52403

    2

    The Orthopaedic Center

    Rockville, Maryland, United States, 20850

    3

    Advanced Orthopedic Specialists

    Cape Girardeau, Missouri, United States, 63701

    4

    Orthopaedic Associates of Rochester

    Rochester, New York, United States, 14626