Status:

COMPLETED

Change in Plaque Characteristics With Atorvastatin

Lead Sponsor:

Wakayama Medical University

Conditions:

Acute Coronary Syndrome

Atherosclerosis

Eligibility:

All Genders

20-75 years

Phase:

PHASE4

Brief Summary

To examine effects of intensive lipid lowering therapy with atorvastatin on stabilization of coronary plaque by using optical coherence tomography (OCT) in patients with acute coronary syndrome.

Detailed Description

Patients with acute coronary syndrome (myocardial infarction or unstable angina) who will undergo PCI and have at least one atherosclerotic lesion of \>25% stenosis other than culprit lesions of curre...

Eligibility Criteria

Inclusion

  • Patients with acute coronary syndrome (myocardial infarction or unstable angina) who will undergo PCI.
  • plasma LDL cholesterol levels : \>=100mg/dL and ≤160mg/dL
  • at least one atherosclerotic lesion of \>25% stenosis other than culprit lesions of current ACS

Exclusion

  • Patients who will undergo coronary bypass surgery.
  • Patients with major complications during treatment of culprit coronary lesions.
  • Patients with an atherosclerotic lesion with \>50% stenosis at a left main trunk.

Key Trial Info

Start Date :

August 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2012

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00700037

Start Date

August 1 2009

End Date

February 1 2012

Last Update

October 29 2014

Active Locations (1)

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Wakayama Medical University

Wakayama, Wakayama, Japan, 641-8509