Status:

WITHDRAWN

Insulin Infusion and Infectious Diabetic Foot Ulcers (IIIFU)

Lead Sponsor:

Karolinska Institutet

Conditions:

Diabetes Mellitus

Insulin Resistance

Eligibility:

All Genders

18+ years

Brief Summary

Normoglycemia is important for the outcome of surgical and medical conditions. Insulin infusions have been studied to achieve normoglycemia during these circumstances and have proved to be useful. Ins...

Detailed Description

Introduction: Normoglycemia is important for the outcome of acute surgical and medical conditions. Different insulin infusions have been studied to achieve normoglycemia and have proved to be useful....

Eligibility Criteria

Inclusion

  • Patients are eligible for inclusion if the following criteria are fulfilled:
  • Postoperative or infectious patients with: skin-, airways-, urine tract- or gastro-intestinal infections.
  • Hyperglycaemia: Capillary P-glucose above 8 mmol/L.
  • Older than 18 years.
  • Informed consent obtained.

Exclusion

  • Patients having any of the following at randomization will not be included in the study:
  • Unconsciousness: not possible to wake up.
  • Ketoacidosis: pH less or equal to 7.30.
  • Hyperosmolar syndrome: S-Na more or equal to 150 mmol/L.
  • Kidney failure: calculated GFR \< 30 mL/min.
  • Pregnancy.
  • Mental condition making the subject unable to understand the concepts and risk of the study.

Key Trial Info

Start Date :

December 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00700362

Start Date

December 1 2011

End Date

December 1 2016

Last Update

October 5 2020

Active Locations (1)

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Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology

Stockholm, Sweden, 171 76