Status:
TERMINATED
Cardiac Resynchronization Therapy, Dyspnea and Exercise Tolerance in Patients With Congestive Heart Failure (CHF)
Lead Sponsor:
Queen's University
Conditions:
Congestive Heart Failure
Eligibility:
All Genders
18-90 years
Phase:
PHASE4
Brief Summary
A new therapy for patients with advanced heart failure (HF) involves the implantation of a specialized pacemaker device (Cardiac Resynchronization Therapy, CRT) that attempts to restore the synchroniz...
Eligibility Criteria
Inclusion
- clinically stable
- being considered for implantation of biventricular pacemaker for CRT
- LVEF \<35%
- QRS duration \>120 msec
- NYHA III-IV functional class
- optimized pharmacologic management of CHF
- no recent (\<1 month) episodes of decompensated CHF
Exclusion
- inability to perform cycle ergometry or comply with testing
- uncontrolled ischemic heart disease
- coronary revascularization within 3 months of study entry
- concurrent primary lung disease
- current use of ambulatory oxygen
- rhythm other than sinus
- dependency on pacemaker therapy as a consequence of bradyarrhythmias
- severe valvulopathy
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT00700700
Start Date
October 1 2008
End Date
June 1 2011
Last Update
July 6 2011
Active Locations (1)
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1
Kingston General Hospital
Kingston, Ontario, Canada, K7L 3N6