Status:
COMPLETED
Study of Intensive Care Unit (ICU)-Acquired Weakness (Handgrip Strength Study)
Lead Sponsor:
Naeem Ali, MD
Conditions:
Peripheral Muscle Strength
Eligibility:
All Genders
18+ years
Brief Summary
To better understand ICU-acquired weakness in patients requiring mechanical ventilation in the Intensive Care Unit.
Detailed Description
We have generated the hypothesis that handgrip strength can be used to develop our understanding of the effects of critical illness on peripheral muscle strength. To begin to develop this hypothesis,...
Eligibility Criteria
Inclusion
- • Adult patients admitted to the Medical ICU
- Age ≥ 18 years of age at ICU admit.
- Requiring mechanical ventilation for at least 24 hours
Exclusion
- • Moribund or in the process of withdrawal of life support
- Patient, family or physicians not in favor of continued support until awakening.
- Profound neurologic injury associated with little or no chance of awakening.
- Active consideration of a diagnosis of brain death by treating physicians.
- Known history of chronic neurological disease resulting in muscle weakness in more than two limbs.
- Inability to perform handgrip dynamometry prior to acute illness.
- Subject is a Non-english speaker
- Subject or surrogate unable to provide informed consent.
- ICU stay of greater than 24 hours within the last thirty days or at any point during the current hospitalization
- Greater than seven days of hospital care prior to hospital admission.
- Greater than five days since inclusion criteria met.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT00702000
Start Date
May 1 2008
End Date
May 1 2010
Last Update
January 18 2016
Active Locations (1)
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1
The Ohio State University
Columbus, Ohio, United States, 43210