Status:

COMPLETED

Efficacy Study of Strattera for Treating Attention Disorders in Traumatic Brain Injury (TBI)

Lead Sponsor:

Craig Hospital

Conditions:

Traumatic Brain INjury

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Atomoxetine is the only medication that is currently approved by the FDA for the treatment of attention deficit hyperactivity disorder in adults. It has gained recent interest as an alternative medica...

Eligibility Criteria

Inclusion

  • History of TBI
  • Moderate to severe TBI as indicated by Glasgow Coma Score (GCS) score of 12 or less; or Post Traumatic Amnesia (PTA) of seven days or more
  • at least one year post injury
  • between the ages of 18-65 (inclusive)
  • symptoms consistent with attentional dysfunction
  • consent to participate in study

Exclusion

  • history of any conditions that would prohibit standard neuropsychological testing
  • non-English speaking (to the extent that would limit ability to complete study measures)
  • prior history of significant psychiatric illness requiring hospitalization
  • epilepsy
  • cardiovascular disease or risks including: dysrhythmias, angina, myocardial infarction, uncontrolled hypertension, valvular heart disease including mitral valve prolapse
  • use of any monoamine oxidase inhibitor or any other drug affecting brain monoamine concentrations
  • severe renal or hepatic impairment
  • pregnant or lactating

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2012

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00702364

Start Date

January 1 2008

End Date

March 1 2012

Last Update

September 15 2014

Active Locations (1)

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1

Craig Hospital

Englewood, Colorado, United States, 80113