Status:

COMPLETED

Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea

Lead Sponsor:

University of Utah

Collaborating Sponsors:

Anecare

Conditions:

Hypercapnia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The proposed study will measure the time from the end of surgery until the time patients meet the discharge criteria from the postoperative anesthesia care unit and the time from the end of surgery un...

Detailed Description

Hypercapnia has been used in conjunction with hyperpnoea to provide a more rapid return of responsiveness after inhaled anesthesia. In our first clinical study with isoflurane we confirmed that the ti...

Eligibility Criteria

Inclusion

  • adults
  • ASA class I-III
  • both genders
  • scheduled to undergo eye surgery at the Moran Hospital.

Exclusion

  • a history of renal or hepatic disease,
  • chronic alcohol or drug abuse,
  • disabling neuropsychiatric disorder,
  • hypersensitivity or unusual response to other halogenated anesthetics,
  • pulmonary hypertension,
  • increased intracranial pressure,
  • seizure disorder
  • personal/familial history of malignant hyperthermia.
  • currently being treated with known hepatic enzyme-inducing drugs (e.g., phenobarbital, dilantin or isoniazid)
  • or with drugs known to alter anesthetic requirements (e.g., opiates, clonidine, alpha2 agonists, alcohol, anticonvulsants, antidepressants, barbiturates, benzodiazepines or other tranquilizers).
  • intolerance to non-steroidal anti-inflammatories.
  • have received general anesthesia within the previous 7 days,
  • received any investigational drug within the previous 28 days,
  • participated in a previous isoflurane or desflurane study
  • Female subjects can be neither pregnant nor breast feeding.

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2008

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT00708526

Start Date

March 1 2008

End Date

November 1 2008

Last Update

November 29 2022

Active Locations (1)

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1

University of Utah

Salt Lake City, Utah, United States, 84132