Status:
COMPLETED
Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans
Lead Sponsor:
Medical University of Vienna
Conditions:
Healthy
Eligibility:
MALE
18-60 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to investigate the effect of hydrocortisone on glucose-induced insulin secretion and sensitivity, by means of an intravenous glucose tolerance test with frequent sampling ...
Detailed Description
Glucocorticoids (mainly cortisol in men and corticosterone in rodents) are secreted in the adrenal cortex under the control of the hypothalamic-pituitary-adrenal (HPA) axis. They are known for and nam...
Eligibility Criteria
Inclusion
- Healthy subjects
- No concomitant medication
- BMI \< 25 kg/m2
- Age: 18-60 years old
Exclusion
- Impaired glucose tolerance or diabetes mellitus
- Hyperthyroidism, hypothyroidism
- Hepatic, renal or cardiovascular diseases
- Malignancies
- History of medical therapy within 3 weeks prior to enrolment into the study
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00709839
Start Date
June 1 2008
End Date
December 1 2008
Last Update
June 1 2011
Active Locations (1)
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1
Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna
Vienna, Austria, A-1090