Status:

COMPLETED

Study With Information Technology (IT) - Aided Preventive Program in Schizophrenia

Lead Sponsor:

Prague Psychiatric Center

Collaborating Sponsors:

Eli Lilly and Company

Conditions:

Schizophrenia

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Information Technology-aided Program of Relapse Prevention in Schizophrenia (ITAREPS) will decrease the number of hospitalizations in patients with schizophrenia or schizoaffective disorder who are tr...

Detailed Description

Title of Study: ITAREPS Trial: A Prospective Randomized Double-blind Controlled Study in IT-aided Mobile Phone-based Relapse Prevention Program in Schizophrenia. Estimated Number of Study Centers an...

Eligibility Criteria

Inclusion

  • Men and women, ages 18 to 60 years, inclusive. Earliest inclusion day is the 18th birthday and the latest is the day before the 61st birthday.
  • A diagnosis of schizophrenia or schizoaffective disorder according to ICD-10 classification.
  • Increased risk for relapse, defined as having at least 1 psychiatric hospitalization for psychosis within the past 3 years and at least 2 psychiatric hospitalizations for psychosis in total (i.e. ≥ 2 hospitalizations).
  • Clinical Global Impression scale - Severity (CGI-S) ≤ 3 at study Visit 1.
  • All patients must be on stable doses of antipsychotic medication during the study entry.
  • Absence of organic mental disorder, mental disorder due to psychoactive substance use or mental retardation.
  • Presence of a cooperating family member, caregiver or other person who is in frequent contact with the patient (at least 4 times a week) and who is willing to participate in the trial.
  • Signed written informed consent. The informed consent process must be documented by signing the informed consent form prior to any study-related procedures.
  • Eligibility for mobile phone communicating.

Exclusion

  • Participation in another relapse prevention program or another interventional clinical trial will be prohibited during the entire participation in the study. Subjects enrolled in observational (non-interventional) trials are not excluded from this study.
  • Hayward compliance rating scale score \< 2 at Visit 1.

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2012

Estimated Enrollment :

146 Patients enrolled

Trial Details

Trial ID

NCT00712660

Start Date

November 1 2008

End Date

March 1 2012

Last Update

April 2 2013

Active Locations (1)

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Prague Psychiatric Center

Prague, Ustavni, Czechia, 181 03