Status:
COMPLETED
Study of Stool Microbiota in Two Diverse Cohorts of Asian and Its Influence on Allergy Development
Lead Sponsor:
National University Hospital, Singapore
Collaborating Sponsors:
Gadjah Mada University
Conditions:
Eczema
Asthma
Eligibility:
All Genders
Brief Summary
This study aims to document prospectively the incidence of allergies of eczema, asthma and allergic rhinitis in 2 diverse cohorts (Singaporean and Indonesian) with contrasting lifestyles and socioecon...
Detailed Description
The main objective of the current study is to establish the relationship of gut microbiota and development of allergy in 2 populations with different socioeconomic status and prevalence of allergy (hi...
Eligibility Criteria
Inclusion
- Pre-delivery evaluation
- Either parent or sibling (ie first degree relative) has a history of atopy. This will be evidenced by a doctor-diagnosis of asthma, allergic rhinitis or eczema AND a positive skin prick test/specific IgE test to any of a panel of common allergens.
- Parents agree to the child's participation in the study and sign the Informed Consent.
- The subject and the parents are willing to comply with procedures and both child and parents are able to keep to scheduled clinic visits.
- Both parents are at contactable range (with valid mobile or land line numbers) for study team to arrange and schedule clinic visits and complete telephone interviews.
- Post-delivery evaluation
- The subject is born full term (at least 37 weeks gestation).
- The subject does not have major congenital malformations/major illness as judged by the doctor.
- The subject is in otherwise good, stable health on the basis of medical history, physical examination.
- Family appears to be able to successfully complete this study.
Exclusion
- The parent is, in the opinion of the investigator, mentally or legally incapacitated, preventing informed consent from being obtained.
- The parent is unable/ unwilling to comply with procedures.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT00713089
Start Date
March 1 2006
End Date
November 1 2009
Last Update
January 8 2014
Active Locations (2)
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1
Gadjah Mada University Hospital
Yogyakarta, Indonesia, 55281
2
National University Hospital
Singapore, Singapore, 119074