Status:

COMPLETED

Compassionate Use of Ceftriaxone in Patients With Amyotrophic Lateral Sclerosis (ALS)

Lead Sponsor:

Drexel University College of Medicine

Collaborating Sponsors:

MDA/ALS Center of Hope

Conditions:

Amyotrophic Lateral Sclerosis

Cerebrospinal Fluid

Eligibility:

All Genders

20-85 years

Brief Summary

Amyotrophic lateral sclerosis is a uniformly progressive and fatal neurodegenerative disorder for which there is no known cure. In a novel attempt to widen the search for potential therapeutic agents,...

Eligibility Criteria

Inclusion

  • Diagnosis of definite or probable ALS by the El Escorial Criteria
  • Participants must be medically able to undergo the study procedures
  • Subjects must have a registered nurse who can administer the drug daily and also inspect the IV site
  • Not Pregnant
  • Willing to pay for the cost of drug, administration, and safety testing
  • Able to give informed consent

Exclusion

  • Patients who are not diagnosed with ALS by a physician
  • Patients unable to give informed consent
  • Patients who have a history of sensitivity to cephalosporin or penicillin antibiotics (such as Ancef, Keflex, Ceclor, Ceftin, Lorabid, Suprax, or Fortaz).

Key Trial Info

Start Date :

June 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2015

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT00718393

Start Date

June 1 2007

End Date

October 1 2015

Last Update

March 9 2017

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