Status:
UNKNOWN
The Evaluation of Thiol Redox Status in Conjunctiva of Dry Eye Patients
Lead Sponsor:
Meiji University of Oriental Medicine
Collaborating Sponsors:
Kyoto Prefectural University of Medicine
Conditions:
Dry Eye Disease
Eligibility:
All Genders
20+ years
Brief Summary
Dry eye disease is related with oxidative stress at the ocular surface. GSH is one of the key factor of protect from oxidative stress. To evaluate thiol status of ocular surface cells by monitoring GS...
Detailed Description
The conjunctival cells are collected by impression cytology. Those cells are stained with 100 mM of monochlorobimane (MCB, M-1381, Molecular Probes, Eugene, OR) and propidium iodide (PI). Fluorescent ...
Eligibility Criteria
Inclusion
- dry eye patients
- control volunteers
Exclusion
- Young (less than 20) patients
- The patients who rejected this study
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2010
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00718926
Start Date
August 1 2008
End Date
March 1 2010
Last Update
July 21 2008
Active Locations (1)
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1
Kyoto Prefectural University of Medicine hospital
Kyoto, Japan