Status:

COMPLETED

The Effect of Protein on Calcium Absorption and Gastric Acid Production

Lead Sponsor:

Yale University

Conditions:

Osteoporosis

Eligibility:

All Genders

18-45 years

Phase:

PHASE4

Brief Summary

We have established that dietary protein is an important regulator of intestinal calcium absorption in humans. However, we do not understand the mechanism by which dietary protein is affecting calcium...

Detailed Description

We have established that dietary protein is an important regulator of intestinal calcium absorption in humans. However, we do not understand the mechanism by which dietary protein is affecting calcium...

Eligibility Criteria

Inclusion

  • Healthy men and women age 18-45 years
  • Caucasian or Asian descent due to increased risk of Osteoporosis

Exclusion

  • gastrointestinal diseases
  • osteoporosis
  • diabetes
  • hypertension
  • liver disease
  • thyroid disorders
  • kidney disease
  • kidney stones
  • cancer
  • heart disease
  • eating disorders
  • obesity
  • hypogonadism
  • amenorrhea
  • oligomenorrhea
  • abnormal serum FSH or estradiol levels
  • birth control medication or other hormone-altering medications
  • pregnancy
  • Lifestyle factors such as:
  • smoking
  • excessive exercise (although moderate exercise is allowed)
  • prescription medications known to influence vitamin D or calcium metabolism or gastric acid
  • excessive body weight change during the past 6 months
  • food allergies
  • unusual eating habits or medically prescribed diets

Key Trial Info

Start Date :

January 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00719160

Start Date

January 1 2005

End Date

May 1 2008

Last Update

March 6 2020

Active Locations (1)

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1

Yale New Haven Hospital Hospital Research Unit

New Haven, Connecticut, United States, 06510