Status:

COMPLETED

Effect of Breathing a Mixture of 92% Oxygen (O2) + 8% Carbon Dioxide (CO2) on Flicker Induced Blood Flow Changes in Ocular Perfusion

Lead Sponsor:

Medical University of Vienna

Conditions:

Flicker-induced Vasodilatation

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

It has been shown that diffuse luminance flicker increases retinal and optic nerve head blood flow. This indicates that a neuro-vascular coupling between neural activity and blood flow exists in the r...

Eligibility Criteria

Inclusion

  • Men and Women aged between 18 and 35 years, nonsmokers
  • Body mass index between 15th and 85th percentile
  • Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
  • Normal laboratory values unless the investigator considers an abnormality to be clinically irrelevant
  • Normal ophthalmic findings, ametropy \< 3 Dpt.

Exclusion

  • Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
  • Treatment in the previous 3 weeks with any drug
  • Symptoms of a clinically relevant illness in the 3 weeks before the first study day
  • Blood donation during the previous 3 weeks

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2009

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00719342

Start Date

July 1 2008

End Date

December 1 2009

Last Update

November 14 2014

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Department of Clinical Pharmacology, Medical University of Vienna

Vienna, Austria, 1090

Effect of Breathing a Mixture of 92% Oxygen (O2) + 8% Carbon Dioxide (CO2) on Flicker Induced Blood Flow Changes in Ocular Perfusion | DecenTrialz