Status:
COMPLETED
Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Disorder of Bone Density and Structure, Unspecified
Eligibility:
FEMALE
12-26 years
Phase:
PHASE2
Brief Summary
Adolescents and young adults with anorexia nervosa (AN) are at high risk for low bone mineral density at a time when healthy adolescents are rapidly accruing bone, with implications for peak bone mass...
Eligibility Criteria
Inclusion
- \- Meet criteria for anorexia nervosa (AN) as described in the Diagnostic and Statistical Manual of Mental Disorders
Exclusion
- Pregnant or nursing
- Hematocrit \< 30%, K \< 3 mmol/L
- Any illness (other than AN) known to affect bone and mineral metabolism such as diabetes, untreated hypo- or hyperthyroidism, or hyperparathyroidism
- History of use of any medicine, such as corticosteroids, known to affect bone density. Subjects who are on estrogen will still be eligible to participate in the study because our data in adult women with AN do not indicate deleterious effects of estrogen in patients receiving rhIGF-
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT00720122
Start Date
July 1 2008
End Date
October 1 2011
Last Update
November 18 2021
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114