Status:
TERMINATED
Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain
Lead Sponsor:
The Cleveland Clinic
Conditions:
Pain
Nausea
Eligibility:
MALE
18-75 years
Phase:
NA
Brief Summary
The investigators are conducting this study to find out if intravenous (injected through the vein) infusion of lidocaine and ketamine administered with general anesthesia is as effective as a paravert...
Detailed Description
Participants will be randomized into one of three study groups; Group 1 - Paravertebral Group - ropivacaine is injected near the spine before surgery. Midazolam and fentanyl are administered intraveno...
Eligibility Criteria
Inclusion
- Age greater than 18 and less than 75 years
- Male
- Unilateral inguinal hernia scheduled for elective open repair
Exclusion
- Incarcerated hernia or urgent procedure
- Reoperation (recurrent hernia)
- Contraindication to regional anesthesia such as:
- Coagulopathy
- Infection at the site of needle insertion
- Pre-existing chronic pain (at any site) requiring treatment
- Contraindication to any study medication (local anesthetic or ketamine)
- History of significant Axis I psychiatric disease (major depressive disorder,bipolar disorder, schizophrenia, etc.)
- Significant hepatic (ALT or AST \> 2 times normal) or renal (serum creatinine \> 2 mg/dl) impairment
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00720330
Start Date
July 1 2008
End Date
February 1 2010
Last Update
March 12 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cleveland Clinic/Hillcrest Hospital
Mayfield Heights, Ohio, United States, 44124