Status:
COMPLETED
A Sedation/Cognition/Electroencephalogram (EEG) Study Using AZD7325 and Comparator.
Lead Sponsor:
AstraZeneca
Conditions:
Healthy Volunteer
Eligibility:
MALE
18-55 years
Phase:
PHASE1
Brief Summary
The purpose of the study is to determine the effects of the compound AZD7325 as compared to lorazepam on sleepiness, concentration and brain activity.
Eligibility Criteria
Inclusion
- Healthy male aged 18 to 55 years on screening
Exclusion
- Clinically significant illness within 2 weeks before the study start
- Enrollment in another concurrent investigational study or intake of an investigational drug within 30 days or intake of an investigational drug within a period of 5 half lives of that drug prior to the screening visit
- Blood loss in excess of 200 mL within 30 days of Day -2, in excess of 400 mL within 90 days of Day -2, or in excess of 1200 mL within 1 year of Day -2
- Clinically relevant abnormalities in physical examinations, vital signs, ECG, clinical chemistry, hematology or urinalysis
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2008
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00720421
Start Date
June 1 2008
End Date
August 1 2008
Last Update
December 10 2010
Active Locations (1)
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1
Centre for Human Drug Research
Leiden, Netherlands