Status:
COMPLETED
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)
Lead Sponsor:
Tufts University
Conditions:
Oxidative Stress
Eligibility:
All Genders
60+ years
Phase:
EARLY_PHASE1
Brief Summary
The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.
Eligibility Criteria
Inclusion
- Healthy subjects (\>60 yr, n=5)
- subjects with metabolic syndrome (\>60 yr, n=5)
- Subjects who has
- high fasting plasma glucose (\>5.6 mmol/L),
- central obesity (waist-hip ratio, \>0.9 for men, \>0.85 for women)
- either high blood pressure (\>130/85 mmHg) or high triacylglycerol (\>1.7 mmol/L) will be selected to have metabolic syndrome.
- normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function
- no history of smoking or alcoholism.
Exclusion
- consume \>7 alcoholic drinks/wk
- taking cholesterol medication or hormone replacement
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00721643
Start Date
July 1 2008
End Date
December 1 2010
Last Update
April 25 2017
Active Locations (1)
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1
Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts, United States, 02111