Status:

COMPLETED

Monitor the Incidence of Congenital Malformations in Infants of Women Who Have Been Treated With Ganirelix (Orgalutran®)(Study 38644)(P05966)(COMPLETED)

Lead Sponsor:

Organon and Co

Conditions:

Pregnancy

Neonates

Eligibility:

FEMALE

18-39 years

Brief Summary

The primary purpose of this study is to collect data on the incidence of congenital malformations in infants of women with an ongoing pregnancy after controlled ovarian stimulation with recombinant fo...

Eligibility Criteria

Inclusion

  • Puregon® (recFSH)/Orgalutran® group:
  • Women with a pregnancy of \>= 16 weeks after Puregon® /Orgalutran® treatment for IVF or ICSI and ET of fresh embryos. Treatment is defined as having had at least one injection of Orgalutran®.
  • Women between 18 and 39 years of age (inclusive) at the day of hCG.
  • Women who are able and willing to sign informed consent.
  • Controls
  • Infants (gestational age \>=16 weeks) of women pregnant after COH using a GnRH agonist in a long protocol for IVF or ICSI and ET of fresh embryos.
  • Infants of women between 18 and 39 years of age (inclusive) at the day of hCG.
  • The most recent 1000 infants delivered prior to January 1, 2001.

Exclusion

  • None

Key Trial Info

Start Date :

November 1 2000

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2005

Estimated Enrollment :

2066 Patients enrolled

Trial Details

Trial ID

NCT00724789

Start Date

November 1 2000

End Date

November 1 2005

Last Update

February 3 2022

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