Status:

COMPLETED

Dietary Control of Type 2 Diabetes: Low-Carbohydrate Mediterranean Diet Versus Low-Fat Diet

Lead Sponsor:

University of Campania Luigi Vanvitelli

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

30-75 years

Phase:

NA

Brief Summary

The major environmental factors that increase the risk of type 2 diabetes, presumably in the setting of genetic risk, are overnutrition and a sedentary lifestyle, with consequent overweight and obesit...

Eligibility Criteria

Inclusion

  • Type 2 diabetes mellitus (ADA criteria)
  • BMI (body mass index) \> 25 kg/M2
  • Hemoglobin A1c (HbA1c) \< 11%; Blood pressure \< 160 (systolic) and 100 (diastolic) mm Hg
  • Triglyceride levels \< 500 mg/dl.

Exclusion

  • Pregnancy or breast-feeding
  • Previous use of insulin or oral antidiabetic drugs
  • Investigational drug within the previous 3 months
  • Use of agents affecting glycemic control (systemic steroids and weight loss drugs)
  • Patients with history of alcohol or illicit drug abuse
  • Patients with liver enzymes higher than three times the upper limit of normal
  • Serum creatinine \> 1.4 mg/dl.

Key Trial Info

Start Date :

June 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

215 Patients enrolled

Trial Details

Trial ID

NCT00725257

Start Date

June 1 2004

End Date

December 1 2007

Last Update

July 30 2008

Active Locations (1)

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1

Department of Geriatrics and Metabolic Diseases

Naples, Italy, 80138