Status:
COMPLETED
Treatment of Non-falciparum Malaria
Lead Sponsor:
Albert Schweitzer Hospital
Conditions:
Acute Non-falciparum Malaria
Eligibility:
All Genders
6-60 years
Phase:
NA
Brief Summary
Patients with non-falciparum infection will be given artemether-lumefantrine for three days and will be followed up for 28 days. Besides efficacy and safety evaluations a substudy on immunology will b...
Eligibility Criteria
Inclusion
- Male or female patients between the age of 6 months and 60 years and with a minimum of 5kg bodyweight
- Presence of uncomplicated malaria confirmed by: i)fever or history of fever in the previous 4 days, and ii)positive microscopy of P. malariae or P. ovale or mixed infection with P.falciparum with parasite density \> 50-200000/μl of blood
- Written informed consent
Exclusion
- Patients with presence of other clinical conditions requiring hospitalization
- Presence of other febrile conditions
- Presence of significant anemia, defined by hemoglobin \< 7g/dl
- Known history of hypersensitivity,allergic or adverse reactions to artemether or lumefantrine
- Intake of any antimalarial or antibiotics with known antimalarial activity in the preceding 2 weeks
- Pregnant and breast feeding females
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00725777
Start Date
July 1 2008
End Date
February 1 2012
Last Update
February 17 2012
Active Locations (1)
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1
Medical Research Unit of the Albert Schweitzer Hospital
Lambaréné, Moyen-Ogooué Province, Gabon, BP 118