Status:
UNKNOWN
Protocol for Primary Fractionated Stereotactic Body Radiation Therapy for Stage T1 - T3N0 Non Small Cell Lung Carcinoma.
Lead Sponsor:
AZ-VUB
Conditions:
Non Small Cell Lung Carcinoma
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The study population will exist of patients with a histological diagnosis of NSCLC, stage T1, T2 or T3NO who are not fit for or who refuse surgery. A prospective data analysis will be performed on tum...
Eligibility Criteria
Inclusion
- Stage T1,T2,T3N0M0 NSCLC, histological confirmation either by biopsy or cytology
- Maximal tumor diameter of 6 cm
- Only T3 lesions based upon thoracic wall involvement
- Informed consent is required
- Life expectancy of at least 6 months
- Age \> 18 y.
- Karnofsky score ≥ 70 or ECOG score ≤ 1
- Inoperable patients or patients refusing surgery
- Patients with measurable lesion (according to RECIST criteria)
Exclusion
- Diagnosis of small cell lung cancer
- Lymph node involvement
- Prior radiotherapy or chemotherapy for lung cancer
- Pregnant or lactating women
- Known allergy for CT contrast
- No FDG-PET
- Mental condition rendering the patient unable to understand the nature, scope, and possible consequences of the study.
- Patient unlikely to comply with protocol, i.e., uncooperative attitude, inability to return for follow-up visits, extreme degradation of lung function tests and patients not likely to complete the study.
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT00727350
Start Date
March 1 2007
End Date
December 1 2012
Last Update
August 4 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
UZ Brussel
Jette, Brussels Capital, Belgium, 1090