Status:
COMPLETED
Radiation Therapy in Treating Patients With Metastatic Spinal Cord Compression
Lead Sponsor:
Cancer Research UK
Conditions:
Spinal Cord Compression
Unspecified Adult Solid Tumor, Protocol Specific
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known which radiation therapy regimen is more effective in treating metastatic spinal cord compression. PURPOSE...
Detailed Description
OBJECTIVES: * To examine whether a phase III randomized study comparing a single-fraction of radiotherapy with multi-fraction radiotherapy is acceptable to clinicians and to patients with metastatic ...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Histologically or cytologically confirmed malignant disease
- Proven diagnosis of metastatic spinal cord compression on MRI or CT scan
- Single site of compression OR multiple sites that can be treated within a single radiation treatment field
- No patient for whom surgery or chemotherapy treatment is more appropriate
- No multiple myeloma as primary cancer
- PATIENT CHARACTERISTICS:
- Life expectancy \> 1 month
- Not pregnant
- Willing and able to complete assessment forms
- Able to give informed consent
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
November 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2009
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00727584
Start Date
November 1 2007
End Date
August 1 2009
Last Update
August 26 2013
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Bristol Haematology and Oncology Centre
Bristol, England, United Kingdom, BS2 8ED
2
Cancer Research UK and University College London Cancer Trials Centre
Northwood, England, United Kingdom, HA6 2RN
3
Glan Clwyd Hospital
Rhyl, Denbighshire, Wales, United Kingdom, LL 18 5UJ
4
Christie Hospital
Manchester, United Kingdom, M20 6UX