Status:
COMPLETED
Docosahexenoic Acid (DHA) Supplementation and Cardiovascular Disease in Men With High Triglycerides
Lead Sponsor:
USDA, Western Human Nutrition Research Center
Collaborating Sponsors:
VA Northern California Health Care System
DSM Nutritional Products, Inc.
Conditions:
Hypertriglyceridemia
Eligibility:
MALE
39-66 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effects of supplementing diets of hyperlipidemic men with DHA (docosahexenoic acid) on risk factors for cardiovascular disease. We hypothesize that supple...
Detailed Description
Cardiovascular disease (CVD) and stroke are the leading causes of mortality in the United States, accounting for more than 38% of all deaths. Elevated total- and LDL- cholesterol, number of total and ...
Eligibility Criteria
Inclusion
- fasting serum triglyceride values of 150-400 mg/dL
- total cholesterol \< 300 mg/dL
- LDL-cholesterol \< 220 mg/dL
- BMI between 22 and 35 Kg/m2
Exclusion
- anti-inflammatory medications including steroids
- antihypertensives
- non sulfonyl urea medications for diabetes mellitus
- drugs that alter serum triacylglycerols and HDL-C levels (i.e. fibrates)
- niacin supplements
- consumers of illegal substances
- consumers of more than 5 drinks of alcohol per week
- more than one fish meal per week
- dietary supplements of fish oil, flaxseed oil or vitamin C or E
Key Trial Info
Start Date :
June 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2005
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00728338
Start Date
June 1 2003
End Date
November 1 2005
Last Update
August 8 2008
Active Locations (1)
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1
Usda, Ars, Whnrc
Davis, California, United States, 95616