Status:
COMPLETED
Brain Activity During Strategic Planning
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18-60 years
Brief Summary
This study will locate areas in the brain that help people devise action plans to carry out complex tasks requiring use of strategy. The ability to plan strategically is impaired in patients who have ...
Detailed Description
OBJECTIVES Efficient behavior requires the ability to generalize from previous experiences. This can be achieved by behavioral strategies. We use many behavioral strategies; some strategies have stri...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects from ages 18 to 60
- Subjects must be right-hand dominant as defined by the Edinburgh Handedness inventory: (R. C. Oldfield, 1971) -Right lateralized handedness quotient of greater than 0.75 will be considered R handed)
- Subjects willing to abstain from caffeine or alcohol for 48 hours prior to the FMRI scanning.
- EXCLUSION CRITERIA:
- Subjects with clinically significant abnormal findings on neurological exam in any of the following neurological domains: cognitive, cranial nerve, motor, sensory, cerebellar functions.
- Subjects who are pregnant (as determined by positive urine pregnancy test)
- Subjects with any finding on the MRI safety questionnaire which prevents them from safely undergoing an MRI scan
- Subjects with metallic dental fillings which are likely to cause MRI artifacts
- Subjects with any history of brain tumor, stroke, head trauma or a vascular malformation as obtained by history or from imaging studies
- Subjects with any history of a severe medical condition, such as cardiovascular disease, which would prevent them from lying flat for up to 120 minutes
- Subjects without the capacity to give informed consent
- Subjects with claustrophobia or other restrictions which prevent them from undergoing a scan in a confined space for up to 60 minutes
Exclusion
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 26 2010
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00728741
Start Date
August 1 2008
End Date
May 26 2010
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892