Status:
COMPLETED
Creatine Augmentation Treatment in Major Depressive Disorder Subjects
Lead Sponsor:
Ewha Womans University
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
19-65 years
Phase:
NA
Brief Summary
Given 1) the established safety with short-term or long-term supplementation of Cr, 2) its potential usefulness in improving brain energy metabolism, 3) the reported abnormality in brain energy metabo...
Eligibility Criteria
Inclusion
- 19-65 year-old male or female
- Major depressive disorder diagnosed by SCID-IV
- Hamilton depression rating scale score \>= 16 at screening
- Written informed consent
Exclusion
- Suicidal idea that needs hospitalization
- Any other axis I psychiatric disorder
- Neurologic disease (eg., epilepsy, infarct, multiple sclerosis, brain tumor)
- IQ below 80
- Inflammatory disease including autoimmune disease
- Taking anti-inflammatory medication
- Serious physical disease
- Substance abuse or dependence history in recent 6 months
- Pregnant or having plan to be pregnant
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
59 Patients enrolled
Trial Details
Trial ID
NCT00729755
Start Date
August 1 2008
End Date
May 1 2012
Last Update
July 5 2017
Active Locations (4)
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1
Holy Family Hospital
Bucheon-si, Gyeonggi-do, South Korea
2
Seoul St. Mary's Hospital
Seoul, South Korea, 137-701
3
Seoul National University Hospital
Seoul, South Korea
4
St. Paul's Hospital
Seoul, South Korea