Status:
TERMINATED
Examining B12 Deficiency Associated With C677T Mutation on MTHFR Gene in Terms of Commonness and Endothelial Function
Lead Sponsor:
Moshe Flugelman
Conditions:
B12 Deficiency Combined With C677T Mutation on MTHFR Gene
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the commonness of the C677T mutation in the MTHFR gene in subjects with B12 deficiency. Also, we'd like to investigate the effect of B12 deficiency combined w...
Detailed Description
we showed that patiebts with B12 deficiency have higher than expected frequency of MTHFR mutation and patients with both abnormalities havean abnormal endothelial function
Eligibility Criteria
Inclusion
- adult males and females of the broad population aged 20-60
- with no symptomatic heart disease/condition
- with Vitamin B12 levels of 150 pmol or less
- which have not received Vitamin B12 supplement treatment before
Exclusion
- Adults suffering from a known heart disease/condition
- any disease the investigator might find as interfering with the process of the experiment
- tumor-oriented diseases
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00730574
Start Date
July 1 2008
End Date
January 1 2012
Last Update
September 10 2014
Active Locations (1)
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1
Carmel Medical Center
Haifa, Israel, 34362