Status:
RECRUITING
Pharmacogenetic Determinants Of Treatment Response In Children
Lead Sponsor:
St. Jude Children's Research Hospital
Collaborating Sponsors:
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
Conditions:
All Malignancies
Children Being Treated for Catastrophic Illness
Eligibility:
All Genders
Brief Summary
To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic ...
Detailed Description
Pharmacogenetics is that discipline devoted to elucidating the genetic determinants of drug response. Particularly in the area of drug metabolism, many genes exhibit genetic polymorphism; that is, a s...
Eligibility Criteria
Inclusion
- Any patients under evaluation/treatment at St. Jude Children's Research Hospital (SJCRH)
- Parents or family members of St. Jude patients
- Non patient volunteers
- All study subjects must provide informed consent for participation
- Assent/Consent of the patient (parent) must be provided prior to attempts made by investigators to enroll a family member of a SJCRH patient
Exclusion
Key Trial Info
Start Date :
August 17 1998
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2034
Estimated Enrollment :
8800 Patients enrolled
Trial Details
Trial ID
NCT00730678
Start Date
August 17 1998
End Date
March 1 2034
Last Update
September 19 2025
Active Locations (1)
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1
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105