Status:
COMPLETED
Infrahepatic Inferior Vena Cava Clamping During Hepatectomy
Lead Sponsor:
Heidelberg University
Conditions:
Hemorrhage
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Intraoperative blood loss is a major concern during hepatic resection, as it has been shown to adversely affect patients' perioperative outcome. Reduction of central venous pressure during parenchymal...
Eligibility Criteria
Inclusion
- Aged 18 years
- Scheduled for elective hepatic resection due to any reason
- American Society of Anesthesiologists (ASA) score I to III
- Written informed consent
Exclusion
- Medical conditions exposing patient at increased risk for not tolerating liver resection:
- Cirrhosis (Child-Pugh B and C)
- (Hereditary) coagulopathy
- Medical conditions exposing patient at increased risk for not tolerating this trial's study interventions:
- Severe heart disease (e.g. severe CAD requiring intervention, NYHA IV)
- Pulmonary hypertension
- Renal insufficiency (serum creatinin \>2mg/dl or \>177µmol/l; conversion factor 88.4 or requiring dialysis)
- Severe hypernatremia (serum sodium \>155mmol/l)
- Severe hyperchloremia
- For female subjects: pregnancy and lactation
- Impaired mental state or language problems
- Participation in other clinical trials or observation period of competing trials interfering with the endpoints of this trial
- Former participation in the clinical trial
- Expected lack of compliance
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT00732979
Start Date
March 1 2008
End Date
December 1 2011
Last Update
May 17 2013
Active Locations (1)
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1
Department of General, Visceral and Transplantation Surgery, University of Heidelberg
Heidelberg, Germany, 69120